ProDom: Automated clustering of homologous domains
نویسندگان
چکیده
منابع مشابه
Automated clustering of homologous domains
The ProDom database is a comprehensive set of protein domain families automatically generated from the SWISS-PROT and TrEMBL sequence databases. An associated database, ProDom-CG, has been derived as a restriction of ProDom to completely sequenced genomes. The ProDom construction method is based on iterative PSI-BLAST searches and multiple alignments are generated for each domain family. The Pr...
متن کاملPredicting gene ontology functions from ProDom and CDD protein domains.
A heuristic algorithm for associating Gene Ontology (GO) defined molecular functions to protein domains as listed in the ProDom and CDD databases is described. The algorithm generates rules for function-domain associations based on the intersection of functions assigned to gene products by the GO consortium that contain ProDom and/or CDD domains at varying levels of sequence similarity. The hie...
متن کاملHomologous association of oppositely imprinted chromosomal domains.
Human chromosome 15q11-q13 encompasses the Prader-Willi syndrome (PWS) and the Angelman syndrome (AS) loci, which are subject to parental imprinting, a process that marks the parental origin of certain chromosomal subregions. A temporal and spatial association between maternal and paternal chromosomes 15 was observed in human T lymphocytes by three-dimensional fluorescence in situ hybridization...
متن کاملProDom and ProDom-CG: tools for protein domain analysis and whole genome comparisons
ProDom contains all protein domain families automatically generated from the SWISS-PROT and TrEMBL sequence databases (http://www. toulouse.inra.fr/prodom.html ). ProDom-CG results from a similar domain analysis as applied to completed genomes (http://www.toulouse. inra.fr/prodomCG.html ). Recent improvements to the ProDom database and its server include: scaling up to include sequences from Tr...
متن کاملThe ProDom database of protein domain families
The ProDom database contains protein domain families generated from the SWISS-PROT database by automated sequence comparisons. It can be searched on the World Wide Web (http://protein.toulouse.inra. fr/prodom.html ) or by E-mail ([email protected]) to study domain arrangements within known families or new proteins. Strong emphasis has been put on the graphical user interface which allows ...
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ژورنال
عنوان ژورنال: Briefings in Bioinformatics
سال: 2002
ISSN: 1467-5463,1477-4054
DOI: 10.1093/bib/3.3.246